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This video discusses use in moderately to severely active RA only. While dosing with methotrexate varies by indication, SIMPONI ARIA® administration instructions apply to all indications except the pediatric indications noted below.
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80 mg/m2 intravenous infusion over 30 minutes at Weeks 0 and 4, then every 8 weeks
Please see the full Prescribing Information for SIMPONI ARIA® for dosing and administration instructions.

Download the Dosing and Administration Guide for more information about dosing
RA=rheumatoid arthritis; USP=United States Pharmacopeia.
References: 1. SIMPONI ARIA® [Prescribing Information]. Horsham, PA: Johnson & Johnson.